Viscosity sensors for the pharmaceutical industry
The pharmaceutical industry operates in an environment with extremely stringent safety, sterility and precision requirements. Therefore measurement technology has to meet these high standards and compliance for production of all pharmaceutical products, formulations and drugs.
From preparation, fermentation and separation, to precise dosing, filling and reaction control, inline viscosity enables production processes to increase quality, efficiency and boost productivity.
Whether it is small samples, reaction flasks, or large volume processing in pipelines and reactors, Hydramotion viscometers measure viscosity at the heart of the fluid. They detect activity at the molecular level, but with highly robust sensors that have the rare combination of both durability and sensitivity.
The material choice and non-contaminating construction of the viscometer ensures the aseptic design provides an inert presence in the fluid. Furthermore, because the measurement technique only relies on microscopic movements of the sensor, any generated energy is negligible and the viscometer remains intrinsically passive to the process or chemical reaction.
 Hygienic complianceCompliant with 1935/2004/EC, all wetted parts are manufactured from 316 SS and suitable for sanitary and sterile settings. The all-welded sensor rod with open construction means easy cleaning with no contaminant traps. Welds are smooth and crevice-free and surface finishes to Ra < 0.4 µm. |
 Sanitary connectionsFor flexible and simple integration Hydramotion viscometers are available with virtually any hygienic fitting to match your existing equipment. Tri-clamp, RJT, IDF, DIN, SMS or Varinline® are all available, plus high pressure flanges and threads for pressurised reactors and pipelines. |
 Clean in place (CIP)CIP and SIP systems are used on a daily basis in most pharmaceutical facilities. All XL7 viscometers are clean-in-place compatible and can be CIP or SIP with almost any cleaning process including steam systems, alkali clean cycles and acid rinses at high temperatures. All with no need to uninstall from the process. |
APPLICATIONS
|
Reactavisc Monitors Structure Formation During Crystallisation
The pharmaceutical industry places a high importance on precise reaction control, as the process is often required to adhere to strict conditions and deliver reproducible results. The leading pharmaceutical company AstraZeneca, encountered difficulties in effectively managing the rheological fluid behaviour during crystallisation and turned to Hydramotion…
|
|---|
|
Reactavisc Provides Scale-Up Framework from Lab to Pilot Plant
A North American research division faced major challenges in measuring oligosaccharides during synthesis reactions. The problems stemmed from the time-consuming nature of offline HPLC molecular weight measurements, which took 4 hours to yield results. This was hindering the scale-up process from laboratory to pilot phase…
|
|
|
24/7 Viscosity from Govisc Supports Downstream Process Scale-Up
Scientists at GlaxoSmithKline collaborated with Hydramotion and Cambridge Reactor Design in pursuit of enhanced insights into their downstream processing operations. The solution was to deploy a filtration and washing robot with viscosity control across their drug research platforms worldwide. By combining real-time machine vision with robotics, this state-of-the-art platform collects all the data needed to understand the filtration and washing processes…
|
|---|
